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The extraction process and proposed mechanisms for GPEVs in treating <t>UVB-induced</t> Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. <t>UVB</t> <t>radiation</t> triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.
Uvb Lamps, supplied by Philips Healthcare, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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86
Philips Healthcare uvb lamp
The extraction process and proposed mechanisms for GPEVs in treating <t>UVB-induced</t> Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. <t>UVB</t> <t>radiation</t> triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.
Uvb Lamp, supplied by Philips Healthcare, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/uvb+lamp/pm42240706-42-8-10?v=Philips+Healthcare
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Philips Healthcare philips ultraviolet b uvb lamp
The extraction process and proposed mechanisms for GPEVs in treating <t>UVB-induced</t> Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. <t>UVB</t> <t>radiation</t> triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.
Philips Ultraviolet B Uvb Lamp, supplied by Philips Healthcare, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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86
Philips Healthcare narrow band uvb lamp
The extraction process and proposed mechanisms for GPEVs in treating <t>UVB-induced</t> Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. <t>UVB</t> <t>radiation</t> triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.
Narrow Band Uvb Lamp, supplied by Philips Healthcare, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 86 stars, based on 1 article reviews
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Philips Healthcare broadband uvb tl 40w 12 rs lamp
The extraction process and proposed mechanisms for GPEVs in treating <t>UVB-induced</t> Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. <t>UVB</t> <t>radiation</t> triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.
Broadband Uvb Tl 40w 12 Rs Lamp, supplied by Philips Healthcare, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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86
Philips Healthcare 9 w uvb lamp
The extraction process and proposed mechanisms for GPEVs in treating <t>UVB-induced</t> Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. <t>UVB</t> <t>radiation</t> triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.
9 W Uvb Lamp, supplied by Philips Healthcare, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/uvb+lamp/pmc13114462-165-7-13?v=Philips+Healthcare
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The extraction process and proposed mechanisms for GPEVs in treating UVB-induced Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. UVB radiation triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.

Journal: Bioactive Materials

Article Title: Gynostemma pentaphyllum -derived extracellular vesicles alleviate skin aging by destabilizing STING

doi: 10.1016/j.bioactmat.2026.03.010

Figure Lengend Snippet: The extraction process and proposed mechanisms for GPEVs in treating UVB-induced Skin aging. Extracellular vesicles derived from Gynostemma pentaphyllum (GPEVs), isolated and purified from fresh whole herb via differential ultracentrifugation, exhibit anti-photoaging properties. UVB radiation triggers the up-regulation of STING, activating the TBK1-CTCF pathway and causing photoaging. GPEVs effectively promote STING degradation, reducing CTCF-mediated aging gene transcription, protecting against UVB-induced skin aging.

Article Snippet: The UVB radiation source consists of four UVB lamps (Philips, Shanghai, China) with a peak intensity at 311 nm.

Techniques: Extraction, Derivative Assay, Isolation, Purification